Brain Zaps Precautions. Given that withdrawal treatment research still has a long way to go, when it comes to managing brain zaps, prevention is key. Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI). Although it is most commonly used to treat depression, obsessive-compulsive disorder (OCD), panic disorder, and post-traumatic stress disorder (PTSD), Zoloft is sometimes prescribed for social phobia and other phobias. my brain zaps seem to be related to Serotonin. Not sure if its too much or too little that cause the zaps. It feels like a little tingle in my head. Some people have brain shivers during Effexor withdrawal, an electric shock sensation that isn't dangerous but can be frightening and uncomfortable. Appearance And Severity Of Brain Zaps. Not all people experience brain zaps, and reports about their intensity vary. They can be mild and disappear quickly. I want to now how the drug zoloft effices the brain? Asked 25 Nov 2011 by puppytimberwolf Updated 5 December 2011 Topics zoloft, depression, post traumatic stress disorder, obsessive compulsive disorder, panic disorder, premenstrual dysphoric disorder, social anxiety disorder, postpartum depression Have you taken the SSRI antidepressant Zoloft (Sertraline) to help with your depression? Millions of people have taken this antidepressant and many have had success with managing depressive symptoms. Brain shakes are sensations that people sometimes feel when they stop taking certain medications, especially antidepressants. You might also hear them referred to as “brain zaps,” “brain. Shortly after taking Zoloft I landed in ER, I could not breathe. After some research I have learned that cardiovascular problems are associated w/this due to interractions from my other presc. Treatment for Lexapro Withdrawal. The treatment depends on whether you plan on continuing Lexapro or stopping it completely. In some cases, the side effects are too extreme or do not go away at all.